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Fig. 5 | Molecular and Cellular Therapies

Fig. 5

From: Interleukin 20 regulates dendritic cell migration and expression of co-stimulatory molecules

Fig. 5

Influence of IL-10 family interleukins on MDDCs migration. a-d The migration of MDDCs towards an AB human serum gradient through an ECM-like coagulate on a membrane with 8-μm pores in a modified Boyden chamber. The MDDCs were incubated with or without addition of IL-19, IL-20, or IL-24 at concentrations (ρIL) of 0.0001, 0.001, 0.01, 0.1, 1.0, or 10 ng/ml for 30 min. a Migration of IL-20-pretreated MDDCs derived. b Migration of IL-19 pretreated-MDDCs. c Migration of IL-24 pretreated-MDDCs. d Summary of the dose-response curves. e Analysis of the role of IL-20 as a chemoattractant for MDDCs where IL-20 applied in the lower chamber (instead of AB serum)

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