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Table 2 Gene ontology analysis of the EVs protein network

From: Proteomic analysis of extracellular vesicles from medullospheres reveals a role for iron in the cancer progression of medulloblastoma

GO-ID

P-VALUE

Description of bioprocess

Proteins

45429

1.86E-05

positive regulation of nitric oxide biosynthetic process

HSP90AB1|HSP90AA1|HBB

20027

8.87E-05

heme metabolic process

IN H BA|HPX

51131

8.87E-05

chaperone-mediated protein complex assembly

HSP90AA1|HSPD1

43066

1.01E-03

negative regulation of apoptosis

TF| HSPD11 HSPA51ANXA51ANGPTL2

55072

2.56E-03

iron ion homeostasis

TF| HPX

45766

3.64E-03

positive regulation of angiogenesis

TF|ANGPTL2

á…Ÿ

á…Ÿ

á…Ÿ

á…Ÿ

GO-ID

P-VALUE

Description of molecular functions

Proteins

51082

3.30E-06

unfolded protein binding

HSP90AB1|HSP90AA1|CCT8|HSPD1|HSPA5

51087

3.16E-05

chaperone binding

TBCE|HSPD1|HSPA5

30235

4.14E-05

nitric-oxide synthase regulator activity

HSP90AB1|HSP90AA1

43498

8.17E-05

cell surface binding

TF|HSPD1|ANXA5

4859

2.71E-04

phospholipase inhibitor activity

ANXA5|ANXA2

  1. The proteins listed in the table are categorized by their bioprocesses and molecular functions -GO Analysis