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Table 3 Clinical trials involving stem cells for retinal dystrophies

From: Neural stem cells: ready for therapeutic applications?

NCT number

Title

Recruitment

Conditions

Interventions

Sponsor/Collaborators

Phases

Enrollment

Start date

Completion date

NCT01344993

Safety and Tolerability of Sub-retinal Transplantation of hESC Derived RPE (MA09-hRPE) Cells in Patients With Advanced Dry Age Related Macular Degeneration

Recruiting

Dry Age Related Macular Degeneration

Biological: MA09-hRPE implantation

Advanced Cell Technology

Phase 1-2

16

April 2011

December 2014

NCT01345006

Sub-retinal Transplantation of hESC Derived RPE (MA09-hRPE) Cells in Patients With Stargardt’s Macular Dystrophy

Recruiting

Stargardt’s Macular Dystrophy

Biological: MA09-hRPE implantation

Advanced Cell Technology

Phase 1-2

16

April 2011

December 2014

NCT01469832

Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt’s Macular Dystrophy (SMD)

Recruiting

Stargardt’s Macular Dystrophy|Fundus Flavimaculatus|Juvenile Macular Dystrophy

Biological: MA09-hRPE implantation

Advanced Cell Technology

Phase 1-2

16

November 2011

December 2014

NCT01625559

Safety and Tolerability of MA09-hRPE Cells in Patients With Stargardt’s Macular Dystrophy (SMD)

Recruiting

Stargardt’s Macular Dystrophy

Biological: MA09-hRPE implantation

CHA Bio & Diostech

Phase 1

3

September 2012

October 2014

NCT01632527

Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Age-Related Macular Degeneration (AMD)

Recruiting

Age Related Macular Degeneration|Macular Degeneration|AMD

Drug: HuCNS-SC cells implantation

StemCells, Inc.

Phase 1-2

16

June 2012

June 2014

NCT01674829

A Phase I/IIa, Open-Label, Single-Center, Prospective Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (MA09-hRPE) Cells in Patients With Advanced Dry Age-related Macular Degeneration (AMD)

Recruiting

Dry Age Related Macular Degeneration

Biological: MA09-hRPE implantation

CHA Bio & Diostech

Phase 1-2

12

September 2012

April 2016

NCT01691261

A Study Of Implantation Of Human Embryonic Stem Cell Derived Retinal Pigment Epithelium In Subjects With Acute Wet Age Related Macular Degeneration And Recent Rapid Vision Decline

Not yet recruiting

Age Related Macular Degeneration

Biological: PF-05206388 implantation

Pfizer|University College, London

Phase 1

10

April 2014

July 2016

NCT02122159

Research With Retinal Cells Derived From Stem Cells for Myopic Macular Degeneration

Not yet recruiting

Myopic Macular Degeneration

Biological: MA09-hRPE implantation

University of California, Los Angeles|Advanced Cell Technology, Inc.

Phase 1-2

Not specified

Not specified

Not specified