From: Neural stem cells: ready for therapeutic applications?
NCT number | Title | Recruitment | Conditions | Interventions | Sponsor/Collaborators | Phases | Enrollment | Start date | Completion date |
---|---|---|---|---|---|---|---|---|---|
NCT00337636 | Study of HuCNS-SC Cells in Patients With Infantile or Late Infantile Neuronal Ceroid Lipofuscinosis (NCL) | Completed | Neuronal Ceroid Lipofuscinosis | Biological: HuCNS-SC | StemCells, Inc. | Phase 1 | 6 | May 2006 | September 2009 |
NCT01005004 | Study of Human Central Nervous System (CNS) Stem Cells Transplantation in Pelizaeus-Merzbacher Disease (PMD) Subjects | Completed | Pelizaeus-Merzbacher Disease | Biological: HuCNS-SC cells implantation | StemCells, Inc. | Phase 1 | 4 | November 2009 | December 2012 |
NCT01151124 | Pilot Investigation of Stem Cells in Stroke | Active, not recruiting | Stroke | Biological: CTX0E03 neural stem cells implantation | ReNeuron Limited | Phase 1 | 12 | June 2010 | March 2015 |
NCT01217008 | Safety Study of GRNOPC1 in Spinal Cord Injury | Completed | Spinal Cord Injury | Biological: hES-derived GRNOPC1 implantation | Asterias Biotherapeutics, Inc. | Phase 1 | 5 | October 2010 | July 2013 |
NCT01238315 | Safety and Efficacy Study of HuCNS-SC in Subjects With Neuronal Ceroid Lipofuscinosis | Withdrawn | Neuronal Ceroid Lipofuscinosis | Biological: HuCNS-SC cells implantation | StemCells, Inc. | Phase 1 | 0 | November 2010 | April 2011 |
NCT01321333 | Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Patients With Thoracic Spinal Cord Injury | Active, not recruiting | Thoracic Spinal Cord Injury|Spinal Cord Injury|Spinal Cord Injury Thoracic|Spinal Cord Trauma | Biological: HuCNS-SC cells implantation | StemCells, Inc. | Phase 1-2 | 12 | March 2011 | December 2015 |
NCT01348451 | Human Spinal Cord Derived Neural Stem Cell Transplantation for the Treatment of Amyotrophic Lateral Sclerosis | Active, not recruiting | Amyotrophic Lateral Sclerosis | Biological: human neural spinal cord stem cells implantation | Neuralstem Inc. | Phase 1 | 18 | January 2009 | August 2014 |
NCT01640067 | Human Neural Stem Cell Transplantation in Amyotrophic Lateral Sclerosis (ALS) | Recruiting | Amyotrophic Lateral Sclerosis | Biological: Human Neural Stem Cells implantation | Azienda Ospedaliera Santa Maria, Terni, Italy|Azienda Ospedaliero Universitaria Maggiore della Carita|Università di Padova Italy | Phase 1 | 18 | December 2011 | September 2016 |
NCT01725880 | Long-Term Follow-Up of Transplanted Human Central Nervous System Stem Cells (HuCNS-SC) in Spinal Cord Trauma Subjects | Enrolling by invitation | Spinal Cord Injury | Observation | StemCells, Inc. | Phase 1-2 | 12 | November 2012 | March 2019 |
NCT01730716 | Dose Escalation and Safety Study of Human Spinal Cord Derived Neural Stem Cell Transplantation for the Treatment of Amyotrophic Lateral Sclerosis | Enrolling by invitation | Amyotrophic Lateral Sclerosis | Biological: Human spinal cord stem cell implantation | Neuralstem Inc. | Phase 2 | 18 | May 2013 | April 2014 |
NCT01772810 | Safety Study of Human Spinal Cord-derived Neural Stem Cell Transplantation for the Treatment of Chronic SCI | Not yet recruiting | Spinal Cord Injury (SCI) | Biological: Human spinal cord stem cells implantation | Neuralstem Inc. | Phase 1 | 8 | May 2014 | March 2016 |
NCT02117635 | Pilot Investigation of Stem Cells in Stroke Phase II Efficacy | Not yet recruiting | Ischaemic Stroke|Cerebral Infarction|Hemiparesis|Arm Paralysis | Biological: CTX DP | ReNeuron Limited | Phase 2 | 41 | June 2014 | June 2017 |