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Figure 1 | Molecular and Cellular Therapies

Figure 1

From: Making sense of how HIV kills infected CD4 T cells: implications for HIV cure

Figure 1

Pathways of CD4 T cell death in HIV infection. Depicted are the described pathways for both uninfected and infected CD4 T cell death in the context of HIV infection and whether progeny virions are produced as a result of the pathway. Examples are provided describing the pathogenicity of the pathway in relevant in vitro models. Specific in vivo support of the pathwaysm biologic relevance are also described. Theoretical ways to inhibit the described pathways are conjectured. References[26–28, 37–44].

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