Table 2 miRNAs profiling studies correlated to drugs response
From: MicroRNAs: short non-coding players in cancer chemoresistance
Cancer type | n° of deregulated miRNAs | Chemoteraupeutic drugs | Reference |
|---|---|---|---|
Breast cancer cell lines chemoresistant vs chemosensi.ve | 137 (63 up, 75 down) | Doxorubicine | [76] |
Breast cancer cell lines chemoresistant vs chemosensi.ve | 15 (8 up, 7 down) | Tamoxifen | [61] |
16 ovarian cancer cell lines | 27 (18 up, 9 down) | Cisplatin, doxorubicine, topotecan, paclitaxel, docetaxel, gemtabicine | [77] |
Ovarian cancer cell lines chemoresistant vs chemosensi.ve | 6 (3 down in all resistant cell lines) | Cisplatin, paclitaxel | [78] |
Ovarian cancer cell lines ALDH + vs ALDH-chemoresistant vs chemosensitive ALDH + cell lines | 6 up | Paclitaxel | [79] |
Lung cancer cell lines chemoresistant vs chemosensi.ve | 7 (5 up, 2 down) | TRAIL | [80] |
Prostate cancer cell lines chemoresistant vs chemosensi.ve | 10 (5 up, 5 down) | Cisplatin, docetaxel | [81] |
Gastric cancer sapmles pre-treated vs normal | 58 | Cisplatin, 5-fluorouracile | [82] |