Table 2 MetaCore Map Folders and Pathways identified in the comparison between TP1 and TP2 (p < 0.01, FDR < 0.05)
Map folder | ╟p-value | †Ratio | Pathway maps | ╟p-value | †Ratio |
|---|---|---|---|---|---|
Immune system response | 2.824e-7 | 21/1000 | Immune response_IFN alpha/beta signaling pathway | 8.104e-5 | 5\24 |
Cell cycle and its regulation | 3.224e-6 | 14/516 | Development_PEDF signaling | 2.255e-2 | 6\53 |
Inflammatory response | 3.794e-6 | 17/775 | Immune response_HMGB1/TLR signaling pathway | 6.734e-4 | 5\36 |
Vascular development (Angiogenesis) | 1.478e-4 | 12/543 | Development_PEDF signaling | 1.689e-2 | 4\49 |
Tissue remodeling and wound repair | 1.882e-4 | 12/557 | Cell adhesion_Cell-matrix glycoconjugates | 4.201e-2 | 3\38 |
Apoptosis | 2.491e-3 | 14/953 | Development_PEDF signaling | 4.224e-3 | 4\49 |
Mitogenic signaling | 1.015e-2 | 9/562 | Development_PEDF signaling | 4.656e-3 | 4\49 |
Transcription regulation | 1.137e-2 | 3/71 | Apoptosis and survival_Role of PKR in stress-induced apoptosis | 4.099e-1 | 3\53 |
Cell differentiation | 1.656e-2 | 12/940 | Some pathways of EMT in cancer cells | 2.340e-2 | 3\51 |
Hypoxia response regulation | 3.269e-2 | 2\43 | Development_EPO-induced PI3K/AKT pathway and Ca(2+) influx | 1.000e + 0 | 2\43 |