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Table 1 Clinical profiles showing age, CD4+, CD8+ T cell counts, plasma viral load and the HAART regimen of patients enrolled in the study

From: Genome-wide analysis of primary peripheral blood mononuclear cells from HIV + patients-pre-and post- HAART show immune activation and inflammation the main drivers of host gene expression

Patients

Age

Time point

CD4 count (cell/μl)

CD8 count (cell/μl)

Viral load (COPIES/ML)

Drugs used during treatment

SC18

27

20/08/96

510-pre

980

112,000

RTV

2 years 07/09/98

710-post

840

< 20

SQV

d4T

3TC

SC19

36

day 3 19/09/96

610-pre

1408

108634

SQV

3 years 08/09/99

720-pos

720

< 20

d4T

3TC

SC 27

33

21/12/96

620-pre

1810

169841

SQV

1.5 years 06/07/98

620-post

1200

< 20

d4T

3TC

SC35

34

19/02/97

750-pre

1380

605236

RTV

2 years 23/03/99

1010-post

840

< 20

SQV

d4T

3TC

SC39

43

04/04/97

n/a

n/a

1602

RTV

3 years 05/04/00

  

< 20

SQV

d4T

3TC

SC40

34

SC peak 18/04/97

600-pre

400

3678

NVP

on + off Rx 16/03/99

800-post

840

< 20

d4T

3TC

SC51

35

pre 28/10/97

400-pre

680

10117

RTV

1 year 28/10/98

810-post

1130

< 20

IDV

d4T

3TC

SC61

25

30/03/98

510-pre

930

6264

RTV

2 years 11/05/00

990-post

870

< 20

IDV

d4T

3TC

SC65

26

20/05/98

360-pre

1380

647095

RTV

2 years 10/05/00

620-post

1217

< 20

IDV

d4T

3TC

SC70

29

16/07/98

650-pre

1069

334088

RTV

3 years 23/04/01

1222post

624

< 20

IDV

d4T

3TC

SC71

31

05/08/98

830-pre

1050

5208

RTV

2 years 13/12/00

1073post

1073

<20

IDV

d4T

3TC

SC75

34

14/09/98

300-pre

1420

92000

RTV

1 year 23/09/99

610-post

861

< 20

IDV

d4T

3TC

SC64

28

14/05/98

1050pre

950

24835

NEV

2 years 21/03/00

1160post

1106

<20

ddI

d4T

3TC

DT 73

32

13/05/98

510-pre

831

142900

RTV

3 year 26/09/00

722-post

399

< 20

IDV

d4T

3TC

  1. Individual drug abbreviations of the prescribed anti-HIV drugs: 3TC (lamivudine); d4T (stavudine); ddI (didanosine); RTV (ritonavir); SQV (saquinavir); NVP (nevirapine); IDV (indinavir); NLF (nelfinavir); NEV (nevirapine). Patients stayed on treatment for 2-3 years in average.
  2. Two time points were used, indicated as pre- and post-therapy in the genome-wide analysis.