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Figure 7 | Molecular and Cellular Therapies

Figure 7

From: Genome-wide analysis of primary peripheral blood mononuclear cells from HIV + patients-pre-and post- HAART show immune activation and inflammation the main drivers of host gene expression

Figure 7

Canonical pathway maps represent a set of about 650 signalling and metabolic maps covering human biology (signalling and metabolism) in a comprehensive way. All maps are drawn from scratch by GeneGo annotators and manually curated and edited. Experimental data is visualized on the maps as blue (for downregulation) and red (upregulation) histograms. The height of the histogram corresponds to the relative expression value for a particular gene/protein (MetaCore™). a) Immune response_Antiviral actions of Interferons pathway; b) Immune response_IFN alpha/beta signaling pathway; c) Immune response_Role of PKR in stress induced antiviral cell response; d) Immune response_HMGB1/TLR signaling pathway; e) Immune response_Role of HMGB1 in dendritic cell maturation and migration.

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Molecular and Cellular Therapies

ISSN: 2052-8426

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