Figure 2

Lopinavir specifically promotes survival of productively HIV-infected CD4 T cells. A) The percent of TUNEL positive cells at day 6 was regressed upon supernatant p24 concentration using linear regression. P < 0.05 considered statistically significant. B) Intracellular HIV p24 expression as a marker of cell infection and cell death (Aqua stain positive) were measured by flow cytometry. Representative results at day 2 post infection of 3 independent experiments. C) The percentage of p24+ cells that co-stained positively for the Aqua dead stain, expressed as the mean +/- standard error for three independent experiments, was compared using ANOVA. *Indicates a p value <0.05, **a p value <0.01 in post-tests between groups.